The impact of IPT was unaffected by patient variables, settings, or site conditions. The mean effects of inpatients and outpatients during the therapy phase are similar to findings reported on other meta-analyses of psychosocial treatments. Symptom-stabilized and postacute patients also displayed significant improvements under IPT.
A historical account of schizophrenia proneness categories from DSM-I to DSM-5 ()
At the beginning of therapy, postacute patients exhibited larger selective attention deficits. This finding is supported by an aggregation of empirical findings on neurocognitive deficits eg, selective attention during the premorbid and remission phases as well as during acute psychotic episodes. With respect to the other patient variables, only duration of illness predicted lower success in IPT. In contrast, the age and the duration of hospitalization predicted the outcome for the control conditions but not IPT.
Considering the small effects of the control interventions, older patients with longer lasting hospitalizations failed to benefit. In comparison, these patients benefited from IPT more than the control conditions. The marginal predictive value of the other patient variables was previously noted by Mojtabai et al. During the s, the frequency of IPT group therapy varied between 2 and 5 sessions a week. In recent years, however, a reduced regime of 2 weekly IPT sessions has become accepted as standard. The use of a combination of only some IPT subprograms for homogeneous groups of selected patients based on a behavioral and problem analysis 31 would appear a reasonable, efficient, and cost-effective treatment approach.
In cases of more heterogeneous groups of patients with impaired functioning across a broader range of domains, only the application of the complete IPT would appear to produce sustainable effects. Furthermore, the broad scope of IPT, including neurocognitive, social cognitive, and psychosocial components, renders it suitable for patients in various states of illness and with rehabilitation needs spanning the entire spectrum of psychiatric care.
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Therefore, IPT may be useful in closing the gap between selective neurocognitive or psychosocial interventions and nonspecific rehabilitation approaches in standard care for schizophrenic patients. The findings of the present meta-analysis are naturally subject to limitations of the methods used in the research and the clinical applications of the IPT model. When reviewing the results of the limited number of studies of outpatients and postacute patients, the statistical testing of these studies had only modest power.
Hence, further replication studies addressing these limitations are desirable. To date, authoritative statements pertaining to differential treatment indication, which also take the individual course of rehabilitation, the impact of therapeutic variables, and relapse prevention into consideration, are lacking, not least owing to the available data pool. In accordance with the National Institute of Mental Health-Measurement and Treatment Research to Improve Cognition in Schizophrenia initiative, 10 , 12—17 the coherence of differentiated functional domains during the course of treatment and aftercare of IPT—especially in the domains of neurocognition and social cognition and its relation to functional and community outcome—should be investigated in further controlled trials utilizing adequate sample sizes.
We would like to thank Ms Lic. Alessandra Colombo for her assistance in the preparation of the manuscript. Oxford University Press is a department of the University of Oxford. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide. Sign In or Create an Account. Sign In. Advanced Search. Article Navigation.
Close mobile search navigation Article Navigation. Volume Article Contents. Volker Roder. Oxford Academic. Google Scholar. Daniel R. Kim T. Hans D. Cite Citation. Permissions Icon Permissions. Abstract Against the background of evidence-based treatments for schizophrenia, nowadays the implementation of specific cognitive and behavioral interventions becomes more important in the standard care of these patients. View large Download slide.
Table 1. View Large. Table 2. Table 3. Table 4. Search ADS. Provision of services for people with schizophrenia in five European regions. Vocational rehabilitation in schizophrenia and other psychotic disorders: a literature review and meta-analysis of randomized controlled trials. Studies of cognitive change in patients with schizophrenia following novel antipsychotic treatment.
The effects of atypical antipsychotic drugs on neurocognitive impairment in schizophrenia: a review and meta-analysis. Biological and cognitive vulnerability factors in schizophrenia: implications for treatment. Implications for the neural basis of social cognition for the study of schizophrenia. Does social cognition influence the relation between neurocognitive deficits and vocational functioning in schizophrenia? Self-efficacy and neurocognition may be related to coping responses in recent-onset schizophrenia.
Cognitive predictors of psychosocial functioning outcome in schizophrenia: a follow-up study of subjects participating in a rehabilitation program. Role of psychosocial treatment in management of schizophrenia: a meta-analytic review of controlled outcome studies. Sind psychosoziale Interventionen bei schizophrenen Patienten wirksam?
Eine Metaanalyse. Psychological treatment in schizophrenia: I. Meta-analyses of family intervention and cognitive behaviour therapy. Cognitive therapy for psychosis in schizophrenia: an effect size analysis. Cognitive rehabilitation in schizophrenia: a quantitative analysis of controlled studies. Approaches to cognitive remediation of neuropsychological deficits in schizophrenia: a review and meta-analysis.
Psychological treatment in schizophrenia: II. Meta-analyses of randomized controlled trials of social skills training and cognitive remediation. Google Preview. A review and critique of social skills training with schizophrenic patients.
Psychotherapie Und Sozialtherapie Der Schizophrenie Ein Internationaler Überblick 1985
Improving recreational, residential, and vocational outcomes for patients with schizophrenia. Development of specific social skills training programmes for schizophrenia patients: results of a multicentre study. Praxishandbuch zur verhaltenstherapeutischen Behandlung schizophren Erkrankter. Kognitive Therapie bei Schizophrenen: Problemanalyse und empirische Ergebnisse. Integriertes psychologisches Therapieprogramm bei chronisch schizophrenen Patienten: Untersuchungen zur Differentialindikation.
Untersuchungen zur Wirksamkeit psychologischer Therapieprogramme in der Rehabilitation chronisch schizophrener Patienten. Kognitive Therapieprogramme bei Patienten mit schizophrener Residualsymptomatik. Ergebnisse der kognitiven Therapie und der Verlauf schizophrener Psychosen im ersten bis zweiten Jahr nach der Entlassung.
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Recent advances in psychiatric rehabilitation for patients with severe mental illness.
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Direct assessment of functional abilities: relevance to persons with schizophrenia. Psychosocial skills training for schizophrenia: lessons from the laboratory. Applications of errorless learning for improving work performance in persons with schizophrenia. Assessment of executive dysfunction during activities of daily living in schizophrenia.
Do specific neurocognitive deficits predict specific domains of community function in schizophrenia? Cognitive training and supported employment for persons with severe mental illness: one-year results from a randomized controlled trial. Treatment research at the crossroads: the scientific interface of clinical trials and effectiveness research. All rights reserved. For permissions, please email: journals. Issue Section:.
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Eingestellte Hypertonie mit normotonen Blutdruckwerten ist kein Ausschlusskriterium. Kognitive Anforderungen, die an das Fahrverhalten gestellt werden, lassen sich nach Michon in drei hierarchisch angeordnete Ebenen unterteilen. Der Effekt von Atomoxetin auf das Fahrverhalten wird in einer standardisierten ca. The controlled group stays untreated, it does not get another medicinal product or a placebo. The trial involves single site in the Member State concerned. Definition of the end of the trial and justification where it is not the last visit of the last subject undergoing the trial.